Contemporary Issues in Heart Failure and Kidney Disease: The Cardiorenal Connection

Nephrocardiology is an emerging field in medicine defined as the study of the bidirectional interconnection between nephrology-related conditions and cardiovascular-related conditions from nine distinct perspectives: pathophysiology, epidemiology, prevention, diagnosis, prognosis, monitoring, therapy, risk factors, and systemic diseases involving both organs—termed the nine pillars of nephrocardiology

This session will begin by defining nephrocardiology and explaining how cardiorenal syndrome is only one important component of this broader field. Through practical, real-world examples, it will explore clinically significant aspects of nephrocardiology that are particularly relevant to heart failure but often overlooked beyond the scope of cardiorenal syndrome.

The session will also provide an update on cardiac-kidney-metabolic (CKM) syndrome, emphasizing its relevance to heart failure prevention and to the management of obesity and metabolic dysfunction in patients who have already developed HF.

Further, the session will examine the specific challenges posed by comorbid advanced chronic kidney disease (CKD) in the management of heart failure therapies—including the emerging role of finerenone—and in the application of heart failure devices (e.g., ICD, CRT, LVAD, CCM, BAT, PA monitoring) in patients with an eGFR <30 mL/min/1.73 m².

Agenda

• Moderator - Mark Drazner, MD, MSc, FHFSA
• Moderator - Maria Rosa Costanzo, MD
• Introductions
• Nephrocardiology: Beyond the Cardiorenal Syndrome - Parta Hatamizadeh, MD, MPH
• Treating Cardio-Kidney-Metabolic Syndrome to Prevent and Manage Heart Failure - chiadi ndumele, MD, PhD
• Managing Heart Failure with CKD: GDMT, Diets and Renal Replacement Therapies - Robert Page II, PharmD, BCPS, FHFSA
• Heart Failure Devices and CKD: Monitoring, Electronic and Mechanical Devices - Mirnela Byku, MD, PhD
• Panel Discussion