Dr. Alpesh N. Amin served as the Associate Dean for Clinical Transformation for UCI Health and the UCI SOM, where he co-leads the activation efforts for UCI’s $1.4B new medical complex in Irvine, CA and provides leadership with UCI University Physicians and Surgeons Medical Group. He is Co-Director and Medical Director for the Institute for Precision Health within the UC Irvine College of Health Sciences. He earned his undergraduate degree in Bioengineering from UC San Diego, his MD from Northwestern University, and his MBA from UC Irvine. 

From 2008 to 2024 he served three-terms, 16-year tenure as the Tom and Mary Cesario Chair of Medicine. Under his leadership the Department grew from 80 to 250 faculty, expanded its GME trainees base by 25%, increased annual research funding from $30M to $130M, and increased clinical productivity from 100K to 750K wRVUs. Committed to academic and clinical excellence and continuous faculty development, the department’s 14 GME programs are fully accredited without any citations and have won the medical student best clerkship for the past five years. A champion of equity and inclusion, Dr. Amin advanced gender (now over 50% women faculty) and ethnic diversity (61%) across the department while maintaining rigorous merit-based recruitment and retention practices. He successfully increased the philanthropic activities in the department with seven endowed chairs, naming of divisions, and other programmatic initiatives across all missions.  

As Interim Chair of the Department of Radiological Sciences, he oversaw a 20–30% increase in faculty and trainee numbers, enhanced diversity, established the Center for Artificial Intelligence in Diagnostic Medicine, and launched a new Interventional Radiology residency program. A nationally recognized leader in Hospital Medicine, Dr. Amin was the founding executive director and chief of Hospital Medicine and Palliative Medicine establishing one of the country’s premier programs and he co-authored Core Competencies in Hospital Medicine by SHM. He also launched a sustainable new Hospice and Palliative Medicine fellowship by raising philanthropic funds. 

He served as President of UCI’s Council of Clinical Chairs during a pivotal period of institutional transformation, leading the adoption of EPIC EMR, the development of a revised funds flow model, and improvements in clinical integration and billing infrastructure. He also co-chaired the advisory group that created the Center for Clinical Research and served as President of the UCI Medical Staff. 

He is founding Chief & Executive Director of Hospital Medicine & Palliative Medicine where he led efforts in programmatic development and protocols in heart failure management, achieved quality metrics and national recognition in care delivery for heart failure patients. 

Internationally, Dr. Amin has advised the Hamad Medical Corporation in Doha, Qatar, on quality improvement initiatives across eight hospitals under the Ministry of Health. He specializes in implementation science, applying data-driven strategies to improve clinical outcomes and operational efficiency. His innovations include tools such as NHCPlus, eConsults, My Happy Blood (a safe anticoagulation app), and a COVID-19 vulnerability scoring system. He is also Co-Founder and Associate Director of ITEQC, a translational research program focused on high-quality, technology-enabled care. 

Dr. Amin is a Master of the American College of Physicians (ACP) and the Society of Hospital Medicine (SHM) and has held leadership roles as President of the Association of Professors of Medicine (APM), ACP All-California, and SGIM California/Hawaii region. He has authored over 320 peer-reviewed publications and co-edited several books. His many honors include being named Physician of the Year by the Orange County Medical Association and the Indian Medical Association of Southern California. He is a fellow of the Heart Failure Society of America. 

Dr. Amin’s leadership is grounded in the values of kindness, integrity, courage, and respect. His vision centers on social justice, inclusive excellence, and creating spaces where all voices are heard and valued.